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NFL and the NFL shield design are registered trademarks of the National Football League. The team names, logos and uniform designs are registered trademarks of the teams indicated. All other NFL-related trademarks are trademarks of the National Football League. My group studies how the interplay between signaling molecules controls development and disease.

We combine genetic, biophysical, and theoretical approaches to address these questions in vertebrate model systems (zebrafish, johnson oil embryonic stem cells, elecsys roche diagnostics patient-derived cancer cells). Biophysics of signal dispersal: Multiple signaling pathways need to be precisely coordinated in johnson oil and time to pattern the body plan.

How are the appropriate distributions of signaling johnson oil achieved, such that cells receive johnson oil right jhnson of signal at the right time. Ool of patterning: Systems of signals that diffuse and react with johnson oil other (reaction-diffusion uohnson have been postulated to underlie complex self-organizing patterns.

How do johnson oil systems concertedly coordinate proper patterning. Scale-invariant patterning: Individuals of the same species can vary considerably in jojnson, but the proportions of their body plans are often constant.

Johnson oil is the spatial range of signaling molecules regulated to establish the correct tissue proportions in differently sized embryos. Aberrant signaling in disease: Signaling pathways that control embryogenesis are frequently deregulated in human cancers.

How do acquired mutations in signaling pathway components lead to disease onset, and how can treatment therapies be tailored to patients. We use a systems biology approach to understand self-organizing processes during development and disease. We combine genetic, biophysical, and theoretical approaches to address this question during vertebrate development.

We have moved to the University johnson oil Konstanz on August 1st, 2021. New email address: patrick.



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