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Tricyclic's is a class of drugs of antidepressants, for example:Cyproheptadine also can intensify the drying effects on moist tissues (such as the eye or mouth) of other medications with anticholinergic properties, for example, dicyclomine (Bentyl) and bethanechol (Urecholine), and probanthine.

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Off-label (non-FDA approved) uses include spasticity associated with spinal cord injury and preventing migraine headaches. Review side effects, dosage, drug and supplement lithium bipolar, and pregnancy and breastfeeding safety information prior to taking this drug. Periactin, the brand name, has been discontinued.

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